مجلة جامعة الزيتونة الدولية للنشر العلمي مجلة علمية، محكمة، شهرية، مفتوحة الوصول
Abstract
Review: The incidence curve of end stage renal disease is in dramatic exaggeration. On the same side in spite of intensive efforts to improve dialysis care events, anemia remains a life threatening problem among hemodialysis patients. Improper follow up and management of patients on dialysis is the main cause of iron deficiency anemia associated with significant morbidity, and increased risk of mortality.
Objectives: This study aimed to evaluate serum levels of Hemoglobin hepcidin and CRP among end stage renal disease patients.
Methods: This study is a cross- sectional study conducted in Kosti city , White Nile State, Sudan, during a period of Jan to April 2019. 104 subjects were selected of them 52 diagnosed as ESRD patients while the other closely matched were represent ted the reference group. The gender among the study groups were 40 males and 12 are female all of them older than 17 years. Hemoglobin, reactive protein and hepcidin were estimated.
Result: The estimated levels of the parameters under investigation when compared with reference value revealed significance increase. There is no correlation between parameters on side and weight, age and sex on other side. Hepcidin and C- reactive protein were significant increased in patients compared to control group.
Conclusion: Serum hepcidin and C- reactive protein were increased reflecting active inflammatory process and iron status abnormality among patients with end stage renal disease on regular hemodialysis this may be attributed to weak points in follow up program regarding nutrition and periodical screening of inflammation screening among those patients.
Key word: ESRD: Hepcidin, C – reactive protein, Dialysis
by :
| Kamaleldin A. A | Mohammed O.Mussa |
| Departments of Biochemistry,Faculty of Medicine, El-imam Elmahdi University, Sudan | Department of Laboratories,Almaramea Medical Center,Kosti,Sudan |
| Daw elbeit A. Y | Fatima. H .M |
| Departments of Biochemistry,Faculty of Medicine, El-imam Elmahdi University, Sudan | Ministry of Education, White Nile State , Sudan |
| Salah E.I | Tarig B.A |
| Departments of Biochemistry,Faculty of Medicine, Managil University of Science and Technology , Sudan | Department of Pathology,Faculty of Medicine,University of Bisha,KSA |
| Amani B.K | |
| Departments of Biochemistry,Faculty of Medicine, El-imam Elmahdi University, Sudan | |
